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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
8.18
Human Site:
S473
Identified Species:
12.86
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
S473
P
P
S
G
T
K
K
S
K
R
G
R
G
R
P
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
S473
P
P
S
G
T
K
K
S
K
R
G
R
G
R
P
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
T500
P
I
R
P
P
S
G
T
K
K
S
K
R
G
R
Dog
Lupus familis
XP_851971
482
53401
K471
I
R
P
P
S
G
T
K
K
S
K
R
G
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
T473
P
I
R
P
P
S
G
T
K
K
S
K
K
G
R
Rat
Rattus norvegicus
P67999
525
59113
P497
G
E
A
S
A
P
L
P
I
R
Q
P
N
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
P454
G
E
A
S
A
P
L
P
I
R
Q
P
N
S
G
Chicken
Gallus gallus
P18652
752
84421
G484
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
T
Frog
Xenopus laevis
P10665
733
82620
Q466
E
I
L
R
R
Y
G
Q
H
P
N
I
I
A
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Q470
E
I
L
M
R
Y
G
Q
H
P
N
I
I
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E1104
T
F
G
T
T
K
R
E
E
N
F
Y
G
F
S
Honey Bee
Apis mellifera
XP_395876
456
51514
E448
G
V
G
H
G
N
V
E
D
T
E
M
I
E
I
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
V508
R
H
S
H
H
Q
F
V
V
K
L
F
D
V
Y
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
A478
T
S
D
G
A
S
N
A
T
A
A
K
T
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S462
T
Y
V
R
P
P
H
S
F
L
H
R
T
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
13.3
26.6
N.A.
13.3
6.6
N.A.
6.6
0
0
0
N.A.
20
0
6.6
6.6
P-Site Similarity:
100
100
33.3
33.3
N.A.
33.3
13.3
N.A.
13.3
13.3
0
0
N.A.
33.3
0
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
20
0
0
7
0
7
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
7
0
0
0
7
0
0
% D
% Glu:
14
20
0
0
0
0
0
14
7
0
7
0
0
7
0
% E
% Phe:
0
7
0
0
0
0
7
0
7
0
7
7
0
7
0
% F
% Gly:
20
0
14
20
7
7
27
7
0
0
14
0
27
14
27
% G
% His:
0
7
0
14
7
0
7
0
14
7
7
0
0
0
0
% H
% Ile:
14
27
7
0
0
0
0
0
14
0
0
14
27
7
7
% I
% Lys:
0
0
0
0
0
20
14
7
34
20
7
20
7
0
0
% K
% Leu:
0
0
14
7
7
0
14
0
0
7
7
0
0
0
14
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
0
7
14
7
14
0
0
% N
% Pro:
27
14
7
20
20
20
0
14
0
14
7
14
0
0
14
% P
% Gln:
0
0
0
0
0
7
0
14
7
0
14
0
0
0
0
% Q
% Arg:
7
7
14
14
14
7
7
0
0
27
0
27
7
20
14
% R
% Ser:
0
7
20
14
7
20
0
20
0
7
14
0
0
20
14
% S
% Thr:
20
0
0
7
20
0
7
14
7
7
0
0
14
14
7
% T
% Val:
0
7
7
0
0
0
7
7
7
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
14
7
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _